Aarkstore Enterprise—Fipronil Survey in China

Fipronil is an outstanding insecticide and has played an important role in pest control in China. However, owing to the harmful effect of fipronil on shellfishes and bees, Chinese government has restricted the use of fipronil in China since 1 October 2009. According to COM’s market survey, almost all fipronil used on rice has been out of the market in China. However, currently, some fipronil producers still have no production license and these producers can evade the government’s market supervision through change the name of fipronil, thus, a small amount of fipronil is still used on rice. It is known that, after Bayer’ fipronil patent expired, attracted by promising market and fat profit, more domestic companies took part in fipronil production, and most of them have on production licenses. Under this situation, most fipronil produced by non-license holders was exported through change product name. In addition, in order to capture the market share, some fipronil manufacturer producers also have entered animal health segment and built fipronil production lines in South America. This report is focused on the aspects of production, consumption & export situation, production technology, cost, raw material supply, production situation of substitutes, patent issues, governmental policy and its implementation effects and its impact on the industry, market risks and opportunities arising from the restriction on the use of fipronil, manufacturers and experts’ responses to restrictiocn in China, etc. The following points are clearly addressed in the report: – The development and technology level of Chinese fipronil industry. – The route and the cost of fipronil manufacturer in China – Patent protection of fipronil in China – The background and regulation details of the restriction on the use of fipronil in China – Production and export situation of every fipronil producer in China – Raw material supply situation of fipronil industry and substitute produciton situation – Domestic consumption of fipronil manufacturer – Responses from every fipronil producers and their plan consequent to the restriction on the use of fipronil in China – Market trend of and impact on fipronil industry from the restriction on the use of fipronil – Policy implementation effects – Market risks and opportunities brought by the restriction on the use of fipronil in China On the basis of the first edition, the second edition highlights the policy implementation effects about the restriction on the use of fipronil, the change situation of its production and consumption structure, the forecast of its production, consumption and exports in the next five years, and market risks and opportunities for investing in fipronil manufacturer, etc. Table of Contents : Executive summary Introduction and methodology I Technology situation of fipronil in China I-1 Fipronil technology development in recent years I-2 Current technology level of fipronil manufacturer I-3 R&D I-4 Patent I-5 Introduction to fipronil researchers in China

Side Effects of Fipronil (Frontline) for Dogs

One of the most popular canine flea control products is Frontline for dogs. Fipronil, a chemical insecticide, is the primary active ingredient in the various Frontline products. While promoted as generally safe, it can have some negative effects on a variety of your dog’s systems. Side Effects and Precautions for Frontline The only potential side effect listed for Frontline products is skin reactions at the site of application. The skin can become red and irritated, causing itching and promoting your dog to lick or scratch at the site. If irritation lasts for several days you should consult your veterinarian. In addition to the side effect, there are several precautions that should be followed when treating your dog with Frontline. Depending upon the Frontline product, it is not recommended for puppies under the age of 10 to 12 weeks. Refer to the product packaging for recommended age restrictions. Again, depending upon the Frontline product, it is not recommended for aged or debilitated dogs. The spray should not be used on pregnant or lactating females. The Fipronil in Frontline can interact with medications or supplements your dog is currently taking. Be sure to discuss this with your veterinarian to avoid any negative consequences. Some dogs have a hypersensitivity to Fipronil, so it is important to avoid Frontline if your dog is sensitive to these products. Concerns About FipronilWhile the typical side effect to Frontline is skin reactions, its active ingredient, Fipronil, lists other potential concerns when used on canines. •Skin problems – As stated earlier, Fipronil can cause irritation to your dog’s skin. This irritation can go beyond simple itching as the scratching can cause ulceration and open sores.•Nervous system damage –Fipronil is a neurotoxin, causing damage to the fleas’ nervous system. It can have the same effect on your dog, causing symptoms such as convulsions, body twitches, loss of appetite, unsteady gait and other effects.•Carcinogen –Fipronil has been shown to cause thyroid cancer in dogs. Because of its carcinogenic qualities, it is important for the person applying the Frontline product to thoroughly wash their hands with soap and warm water to adequately remove the product from their skin.•Organ damage – Autopsies have shown an accumulation of Fipronil in canine livers and kidneys, causing an increase in organ weight. Fipronil has also been shown to alter the levels of hormone secreted by the thyroid gland.•Infertility –Fipronil has also been shown to have an effect on a dog’s fertility. Its use has led to smaller litter size, difficulty in conception, decreased litter weights and increase in litter deaths.While Frontline products have had successful use in the control of flea populations, there have been negative results seen when dogs have been maintained for extended periods on the products. The fipronil builds up in your dog’s body, giving it the chance to cause problems. If Frontline is your choice for flea control, consider taking a 3 to 6 month break during low flea infestation periods to allow your dog’s body to rid itself of any toxic build up that may have occurred. This will help to avoid the potential of any problems arising from the fipronil.