Pyrazol: Sildenafil, Riociguat, Rimonabant,
Fipronil,
Zaleplon, Celecoxib, Fomepizol, Tartrazin, Allopurinol, Acetazolamid, Apixaban
Product DescriptionKapitel: Sildenafil,
Riociguat, Rimonabant, Fipronil, Zaleplon, Celecoxib, Fomepizol, Tartrazin,
Allopurinol, Acetazolamid, Apixaban, Pyrazophos, Acibenzolar-S-Methyl,
Stanozolol, Ocinaplon, Pyrazole, Indazol, Tris(pyrazolyl)borate. Aus Wikipedia.
Nicht dargestellt. Auszug: Sildenafil citrate, sold as Viagra, Revatio and
under various other trade names, is a drug used to treat erectile dysfunction
and pulmonary arterial hypertension (PAH). It was developed and is being
marketed by the pharmaceutical company Pfizer. It acts by inhibiting cGMP
specific phosphodiesterase type 5, an enzyme that regulates blood flow in the
penis. Since becoming available in 1998, sildenafil has been the prime
treatment for erectile dysfunction; its primary competitors on the market Fipronil
are tadalafil (Cialis) and vardenafil (Levitra). Sildenafil (compound
UK-92,480) was synthesized by a group of pharmaceutical chemists working at
Pfizer’s Sandwich, Kent, research facility in England. It was initially studied
for use in hypertension (high blood pressure) and angina pectoris (a symptom of
ischaemic heart disease). The first clinical trials were conducted in Morriston
Hospital in Swansea. Phase I clinical trials under the direction of Ian
Osterloh suggested that the drug had little effect on angina, but that it could
induce marked penile Fipronil
manufacturer erections. Pfizer therefore decided to market it for erectile
dysfunction, rather than for angina. The drug was patented in 1996, approved
for use in erectile dysfunction by the US Food and Drug Administration on March
27, 1998, becoming the first oral treatment approved to treat erectile
dysfunction in the United States, and offered for sale in the United States
later that year. It soon became a great success: annual sales of Viagra in the
period 1999-2001 exceeded $1 billion. The British press portrayed Peter Dunn
and Albert Wood as the inventors of the drug, a claim that Pfizer disputes.
Their names are on the manufactur. . . http://booksllc. net/?l=de
